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Table 1 Spine/filopodia and filopodia/spine ratios of rat primary hippocampal neurons overexpressing different SHANK3 variants

From: Phenotypic and functional analysis of SHANK3 stop mutations identified in individuals with ASD and/or ID

Fusion protein

Spines/filopodia

Filopodia/spines

Control

2.70

0.37

SHANK3

2.15

0.47

G1527A

1.32

0.76

2497delG

0.94

1.07

A5008T

3.26

0.31

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Molecular Autism

ISSN: 2040-2392