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Table 3 The distributions of haplotypes in ASD and controls

From: Deep exon resequencing of DLGAP2 as a candidate gene of autism spectrum disorders

 

Haplotype

Cases (frequency)

Controls (frequency)

Chi2

Fisher's P

Pearson's P

Odds ratio (95%CI)

1

A C A C A A G G T

8.84 (0.012)

28.20 (0.036)

7.081

0.007814a

0.007806a

0.367 (0.170 to 0.790)

2

C C A C C A A C C

41.17 (0.057)

63.13 (0.080)

1.548

0.213443

0.213365

0.768 (0.506 to 1.165)

3

C C A C C A A C T

84.15 (0.117)

60.19 (0.076)

11.981

0.000542a

0.000541a

1.880 (1.310 to 2.698)

4

C C A C C A G G C

12.99 (0.018)

26.04 (0.033)

2.331

0.126865

0.126793

0.592 (0.300 to 1.168)

5

C C A C C A G G T

86.66 (0.121)

89.80 (0.114)

1.380

0.240147

0.240071

1.218 (0.876 to 1.694)

6

C C A T C A A C T

27.74 (0.039)

25.95 (0.033)

0.973

0.324045

0.323985

1.319 (0.759 to 2.292)

7

C G G C A A A C T

31.96 (0.045)

32.97 (0.042)

0.465

0.495147

0.495131

1.192 (0.719 to 1.976)

8

C G G C A A G G C

30.14 (0.042)

45.29 (0.057)

0.902

0.342270

0.342214

0.792 (0.490 to 1.282)

9

C G G C A A G G T

60.91 (0.085)

81.38 (0.103)

0.381

0.537097

0.537090

0.892 (0.622 to 1.281)

10

C G G C A G G C T

19.59 (0.027)

37.66 (0.048)

2.960

0.085418

0.085359

0.613 (0.349 to 1.076)

  1. ASD, autistic spectrum disorders; Global result: total control = 788.0, total case = 718.0; global chi2 is 26.804893 while df = 9 (frequency < 0.03 in both control and case has been dropped). Fisher's P value is 0.001537. Pearson's P value is 0.001507. Note: aP ≤ value 0.05.