From: Is metabotropic glutamate receptor 5 upregulated in prefrontal cortex in fragile X syndrome?
Binding parameters | Healthy | Fragile X | ||
---|---|---|---|---|
 | (n = 17)a | (n = 14)a | % change | P |
Receptor density (fmol/mg protein) | 1410 ± 421 | 1683 ± 372 | 16 | 0.058 |
Dissociation constant (nM) | 10.6 ± 4.0 | 10.2 ± 1.6 | -4 | 0.293 b |
Binding potential (receptor density/dissociation constant) | 14 ± 5 | 17 ± 4 | 17 | 0.092 |