Figure 2From: Is metabotropic glutamate receptor 5 upregulated in prefrontal cortex in fragile X syndrome?Correlation between mGluR5 density and expression in prefrontal cortex of FXS individuals and healthy controls. mGlur5 density by binding assay and expression by Western blotting positively correlated with a Pearson r = 0.43 and P = 0.018. Healthy controls and FXS full mutations are shown by open (○) and closed circles (●) respectively. The three FXS carriers and one carrier with FXTAS are shown by solid (▲) and semisolid () triangles, respectively. The regression line was determined using linear regression.Back to article page