Fig. 3

Analysis of atypical FC patterns in ASD subtypes. A Results of two-sample t tests for significant differences in FC at the region level for subtype 1, subtype 2, and TC (p < 0.05, FDR corrected). B Differences in FC of subtype 1, subtype 2, and TC at the network level. The upper right and lower left triangles indicate the average network FC values for the different groups. ± indicates a significant increase or decrease in FC for the group in the upper right compared to the group in the lower left (two-sample t tests, p < 0.05, FDR corrected). C Differences in FC of subtype 1, subtype 2, and TC at the whole-brain level. *represents significant differences (two-sample t tests, p < 0.05, Bonferroni corrected). FC, Functional connectivity; ASD, autism spectrum disorder; FDR, false discovery rate; TC, typical controls; SMN, somatosensory network; CO, cingulo-opercular network; AN, auditory network; DMN, default-mode network; VN, visual network; FPN, fronto-parietal network; SAN, salience network; SUB, subcortical network; VAN, ventral attention network; DAN, dorsal attention network; and UND, uncertain network