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Fig. 1 | Molecular Autism

Fig. 1

From: Inter-individual heterogeneity of functional brain networks in children with autism spectrum disorder

Fig. 1

Flowchart of the inter-individual deviation of functional connectivity (IDFC) analysis. A Flowchart of IDFC matrix calculation. The IDFC matrix between the autism spectrum disorder (ASD) group and the typical controls (TC) group can be calculated from the functional connectivity (FC) network. d: the cosine distance between Fik and Fjk; V_roi: IDFC matrix at the region level; and V_net: IDFC matrix at the network level. B ASD subtypes were obtained by a k-means clustering analysis at the network level by using the IDFC at the network level as features. C A multivariate support vector regression model was used to analyze the relationship between network-level IDFC and severity of clinical symptoms of ASD. D The within-group inter-individual FC deviation of the ASD and TC groups was calculated and compared. Vaa_roi: the matrix of inter-individual FC deviation within the ASD group at the region level; Vtt_roi: the matrix of inter-individual FC deviation within the TC group at the region level

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