Molecular Autism

Table 2 SVM results: SVM frequency of assigned group/class and predicted probabilities. Groups presented in order of classification accuracy

From: Profiles of autism characteristics in thirteen genetic syndromes: a machine learning approach

Genetic syndromes
Genetic syndrome		AS		FXS		PWS		RTS		CdLS		DS		CdCS		1p36		LS		SMS		TSC		SS		PMS	Total
	n	Prob	n	Prob	n	Prob	n	Prob	n	Prob	n	Prob	n	Prob	n	Prob	n	Prob	n	Prob	n	Prob	n	Prob	n	Prob	n
AS	130	0.48	7	0.02	6	0.02	1	0.02	28	0.10	6	0.03	15	0.14	5	0.08	9	0.07	5	0.06	3	0.04	8	0.10	1	0.02	224
FXS	4	0.06	237	0.42	41	0.13	7	0.05	30	0.13	7	0.10	14	0.11	9	0.10	38	0.21	25	0.16	27	0.17	5	0.12	18	0.26	462
PWS	1	0.04	35	0.14	219	0.41	8	0.07	39	0.11	60	0.29	9	0.09	3	0.08	15	0.14	9	0.12	26	0.16	5	0.08	15	0.21	444
RTS	0	0.01	1	0.03	0	0.02	78	0.63	0	0.02	0	0.02	0	0.01	0	0.02	0	0.02	1	0.02	0	0.02	0	0.02	0	0.03	80
CdLS	12	0.12	12	0.09	3	0.08	7	0.05	97	0.30	5	0.08	7	0.12	13	0.13	15	0.13	8	0.13	19	0.15	15	0.14	3	0.10	216
DS	1	0.02	5	0.06	9	0.12	1	0.03	3	0.06	55	0.29	2	0.05	2	0.06	5	0.07	0	0.04	2	0.08	1	0.06	3	0.10	89
CdCS	5	0.07	0	0.02	0	0.02	0	0.01	2	0.04	2	0.02	28	0.29	1	0.05	1	0.03	2	0.05	0	0.02	0	0.03	0	0.02	41
1p36	0	0.03	0	0.02	0	0.01	0	0.02	0	0.03	0	0.02	0	0.02	8	0.20	0	0.03	0	0.02	0	0.04	0	0.08	0	0.02	8
LS	0	0.04	0	0.07	0	0.05	0	0.03	0	0.06	0	0.04	0	0.05	0	0.08	6	0.14	0	0.08	0	0.07	0	0.06	0	0.05	6
SMS	0	0.02	0	0.04	0	0.03	0	0.02	0	0.04	0	0.02	0	0.03	0	0.05	0	0.04	4	0.20	0	0.03	0	0.03	0	0.03	4
TSC	1	0.04	0	0.05	0	0.05	0	0.03	0	0.06	0	0.05	0	0.04	0	0.07	0	0.06	0	0.05	6	0.16	0	0.09	0	0.07	7
SS	0	0.01	0	0.03	0	0.03	0	0.02	0	0.03	0	0.03	0	0.02	0	0.03	0	0.03	0	0.03	0	0.04	1	0.15	0	0.02	0
PMS	0	0.04	0	0.02	0	0.01	0	0.02	0	0.03	0	0.01	0	0.02	0	0.08	0	0.02	0	0.02	0	0.04	0	0.03	0	0.06	1
Total	154		297		278		102		199		135		75		41		89		54		83		35		40		1582
Accuracy (%)	130/154 (84%)		237/297 (80%)		219/278 (79%)		78/102 (77%)		97/199 (49%)		55/135 (41%)		28/75 (37%)		8/41 (20%)		6/89 (7%)		4/54 (7%)		6/83 (7%)		1/35 (0.3%)		0/40 (0%)		868/1582 (55%)

AS Angelman syndrome, CdCS Cri du Chat syndrome, 1p36 1p6 deletion syndrome, CdLS Cornelia de Lange syndrome, FXS Fragile X syndrome, PWS Prader–Willi syndrome, LS Lowe syndrome, SMS Smith–Magenis syndrome, DS Down syndrome, SS Sotos syndrome, RTS Rubinstein–Taybi syndrome, TSC Tuberous sclerosis complex, PMS Phelan-McDermid syndrome, Prob Predicted Probability, N Sample size
Bold in each row correspond to the predicted probability and the number of individuals assigned to the syndrome group for this particular group

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