Table 1 Summary of behavioral alterations in Fmr1^−/y-PV and Fmr1⁻.^/y-SOM mice compared to control

Motor function and learning

Rotarod

Not shown (no deficit)

Anxiety-like behavior

Elevated plus maze

Increased time in closed arms and decreased time in the center

–

ASD-like behavior

Marble burying

–

–

Self-grooming

–

–

Y Water Maze

Increased errors during training

–

Sociability and social novelty

Deficit in social novelty behavior

–

Learning and memory

Novel object recognition

–

–

Object location memory

–

Not done

Morris water maze

–

–

Threat conditioning

Increased freezing during tone presentation (CS testing and reconsolidation)

–