Skip to main content

Table 3 Sensitivity, specificity, AUC, PPV, NPV, and Cohen’s kappa between ASD and non-ASD based on ASD cutoff criteria

From: Diagnostic validity of Autism Diagnostic Observation Schedule, second edition (K-ADOS-2) in the Korean population

 Module

n

Sensitivity (%)

Specificity (%)

AUC

PPV (%)

NPV (%)

Cohen’s kappa (p-value)

Total Modules

2158

98.1

90.5

.94

95.7

95.7

.89 (p < .001)

Toddler Module

289

87.5

95.9

.92

91.3

93.9

.84 (p < .001)

  Toddler Module (12–20/NV21–30)

206

85.4

96.8

.91

94.6

90.9

.84 (p < .001)

  Toddler Module (21–30 SW)

83

100.0

94.2

.97

77.8

100.0

.85 (p < .001)

Module 1

642

98.2

84.6

.91

97.9

86.8

.84 (p < .001)

  Module 1 (NW)

314

97.9

92.6

.95

99.3

80.6

.85 (p < .001)

  Module 1 (SW)

328

98.6

80.4

.90

96.5

91.1

.83 (p < .001)

Module 2

574

99.2

91.4

.95

96.0

98.3

.92 (p < .001)

  Module 2 (< 5 yo)

350

98.9

92.7

.96

93.9

98.7

.92 (p < .001)

  Module 2 (≥ 5 yo)

224

99.5

81.8

.91

98.0

94.7

.87 (p < .001)

Module 3

411

99.6

87.1

.93

91.0

99.4

.88 (p < .001)

Module 4

242

99.0

88.0

.94

96.9

95.7

.90 (p < .001)

  1. Notes AUC, Area under curve; PPV, positive predictive value; NPV, negative predictive value; ASD, autism spectrum disorder; 12–20/NV21–30, 12–20 months toddlers/nonverbal 21–30 months toddlers; 21–30 SW, 21–30 months toddlers with some words; NW, no words; SW, some words; and yo, years old