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Table 3 Vertex-wise results for surface-based brain measures for the left and right hemisphere (LH and RH)a

From: The longitudinal bidirectional relationship between autistic traits and brain morphology from childhood to adolescence: a population-based cohort study

Model

Anatomical region

Area size (mm2)

MNI

N vertices

Cluster-wise

ß-value

Cluster-wise

p value

x

y

z

Gyrification LH (N = 1927)

        

 1

Pars opercularis

10,089.32

− 50.3

9.2

5.0

146,256

− 0.031

0.0001

 

Superior frontal

3204.78

− 12.5

53.1

3.1

4925

− 0.012

0.0001

 

Inferior parietal

1029.14

− 38.2

− 50.8

33.6

2567

− 0.016

0.0001

 2

Pars opercularis

1105.75

− 39.8

9.9

22.5

2320

− 0.027

0.0001

Gyrification RH (N = 1927)

        

 1

Superior temporal

7994.05

60.7

− 2.3

− 4.8

18,232

− 0.035

0.0002

 

Rostral middle frontal

590.66

23.8

57.5

6.6

804

− 0.012

0.0027

 2

Insula

420.30

34.7

5.5

3.6

1040

− 0.030

0.0105

 

Superior temporal

409.96

62.2

− 5.8

− 2.9

893

− 0.031

0.0113

Surface area LH (N = 1950)

        

 1

Superior frontal

423.91

− 11.7

64.3

11.3

632

− 0.019

0.0002

 

Insula

391.15

− 38.5

− 6.3

− 16.4

1093

− 0.007

0.0002

 

Precentral

318.22

− 35.7

− 21.3

36.6

817

− 0.005

0.0003

 

Inferior temporal

270.96

− 46.2

− 8.0

− 40.1

446

− 0.022

0.0009

 

Middle temporal

230.11

− 57.8

− 17.9

− 17.1

371

− 0.021

0.0027

 

Superior frontal

151.19

− 22.2

20.1

54.9

201

− 0.028

0.0228

Surface area RH (N = 1950)

        

 1

Postcentral

506.62

16.9

− 32.9

62.0

1271

− 0.006

0.0001

 

Middle temporal

476.04

58.5

− 15.4

− 17.9

767

− 0.015

0.0001

 

Superior frontal

334.18

18.5

5.0

62.2

646

− 0.021

0.0001

 

Insula

246.06

35.7

− 5.6

− 6.2

596

− 0.008

0.0012

 

Lateral occipital

202.13

32.8

− 89.7

− 4.7

245

− 0.019

0.0047

 2

Middle temporal

185.50

57.8

− 16.1

− 17.7

289

− 0.012

0.0085

 

Postcentral

185.42

16.4

− 33.0

61.4

511

− 0.004

0.0085

Cortical thickness LH (N = 1950)

        

 1

Superior frontal

239.46

− 10.1

24.7

56.7

427

0.029

0.003

 2

Superior frontal

220.52

− 10.1

24.7

56.7

397

0.028

0.005

  1. aModel 1 is adjusted for sex, handedness, age at SRS and the difference in age between SRS and MRI; Model 2 is additionally adjusted for child ethnicity, maternal education, maternal smoking and drinking during pregnancy. The effects are standardized