Globally elevated excitation–inhibition ratio in children with autism spectrum disorder and below-average intelligence

Table 1 Characteristics of the experimental samples

Sample	TD	ASD_>85	ASD_<85
Eyes-open condition
N subjects	49	30	19
Age, years	10.81 ± 2.37	10.29 ± 2.95	10.57 ± 2.14
MPI IQ	121.57 ± 12.19	100.37 ± 12.31	69.26 ± 9.36
SRS¹	42.1 ± 22.04 (N = 48)	98.22 ± 23.98 (N = 27)	110.06 ± 20.57 (N = 18)
Eyes-closed condition
N subjects	45	23	15
Age, years	10.73 ± 2.30	10.73 ± 3.12	10.05 ± 2.02
MPI IQ	120.78 ± 12.16	99.43 ± 12.97	71.60 ± 8.77
SRS	41.3 ± 22.16 (N = 45)	97.65 ± 25.27 (N = 20)	111.85 ± 18.69 (N = 14)

TD, typically developing children; ASD, children with autism spectrum disorder; MPI, Mental Processing Index; ASD_>85, children with ASD and MPI above 85; ASD_<85, children with ASD and MPI below 85; and SRS, Social Responsiveness Scale
¹The number of participants for whom information on the SRS questionnaire was available is given in parentheses

ISSN: 2040-2392