Fig. 3
Tbr1+/− mice do not display excessive grooming behaviour nor heightened anxious behaviour. A Heat maps representing the example movements of animals during the light and dark anxiety test. B, C Tbr1+/− mice do not show more anxious behaviour than WT mice, indicated by no differences in the latency to enter the bright arena and time spent in the bright arena, and this is not altered by dietary zinc supplementation. (Sample size: WT30ppm = 14, Tbr+/−30 ppm = 14, WT150ppm = 10, Tbr+/−150 ppm = 11). D Tbr1+/− mice do not show excessive grooming behaviour, measured by per cent time spent grooming, and this is not +/−+/− modified by high dietary zinc. (Sample size: WT30ppm = 15, Tbr30 ppm = 11, WT150ppm = 10, Tbr150 ppm = 11). Each point represents data from individual mice in each experimental group. All data represent mean ± standard error of the mean, analysed using one-way analysis of variance with Tukey’s post hoc test