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Table 1 Demographic and clinical data

From: Two neuroanatomical subtypes of males with autism spectrum disorder revealed using semi-supervised machine learning

  Site 1 (GU) Site 2 (KKI) Site 3 (OHSU) Site 4 (PITT) Site 5 (TRINITY) Site 6 (UCLA) Site 7 (USM)
  HC ASD HC ASD HC ASD HC ASD HC ASD HC ASD HC ASD
N 22 25 66 28 41 35 21 20 25 22 35 38 44 53
Type (A/AS/P/NA) 0/0/0/25 11/16/1/0 0/0/0/35 20/0/0/0 8/7/7/0 32/0/0/6 45/0/1/7
Age 10.8 ± 1.7 11.1 ± 1.7 10.5 ± 1.3 10.3 ± 1.6 10.3 ± 1.5 11.7 ± 2.1 19.3 ± 7.1 19.9 ± 7.2 17.1 ± 3.8 17.1 ± 3.6 12.8 ± 2.3 13.0 ± 2.3 21.6 ± 7.5 22.1 ± 7.1
IQ
 FIQ 121 ± 12.0 121 ± 12.9 114 ± 11.2 106 ± 14.1 114 ± 13.1 109 ± 15.5 110 ± 9.1 113 ± 14.1 111 ± 12.2 110 ± 13.1 107 ± 11.2 103 ± 11.4 115 ± 13.3 104 ± 15.1
 VIQ 122 ± 13.0 123 ± 11.5 119 ± 11.0 113 ± 15.0 108 ± 10.3 110 ± 13.0 110 ± 13.7 109 ± 14.0 109 ± 11.3 105 ± 13.2 113 ± 13.5 100 ± 16.1
 PIQ 117 ± 15.0 117 ± 14.2 113 ± 12.9 107 ± 15.0 108 ± 10.0 112 ± 14.3 110 ± 9.1 110 ± 10.9 104 ± 12.3 101 ± 13.2 114 ± 13.3 107 ± 14.9
ADOS
 Total 10.3 ± 5.0 10.6 ± 1.8 9.0 ± 3.3 12.0 ± 3.1 10.3 ± 2.9 11.1 ± 3.7 12.5 ± 3.1
 Comm 2.9 ± 1.7 3.2 ± 0.6 2.8 ± 1.3 4.1 ± 1.0 3.3 ± 1.5 4.3 ± 1.4
 Social 7.4 ± 3.8 7.4 ± 1.5 6.2 ± 2.2 8.0 ± 2.4 7.8 ± 2.7 8.2 ± 2.3
 RRB 1.6 ± 1.6 2.8 ± 1.6 2.1 ± 1.1 2.5 ± 1.5 1.7 ± 1.8 1.6 ± 1.5
 Severity 5.7 ± 2.7 6.9 ± 2.0 7.2 ± 1.3 6.9 ± 2.3 8.1 ± 2.0
ADI-R
 Social 19.0 ± 4.9 19.8 ± 6.1 20.1 ± 5.1 20.9 ± 3.0 20.2 ± 6.3 20.4 ± 4.7
 Verbal 14.3 ± 3.9 15.4 ± 4.7 16.8 ± 4.4 15.8 ± 3.7 16.4 ± 5.0 16.4 ± 4.6
 RRB 5.0 ± 2.3 6.4 ± 2.3 6.3 ± 2.6 6.6 ± 2.4 5.6 ± 2.7 7.2 ± 2.2
SRS
 Total 20.1 ± 16.0 86.2 ± 35.3 16.4 ± 9.5 93.6 ± 32.3 20.2 ± 15.7 95.3 ± 27.1 16.8 ± 13.1 95.8 ± 33.6
 Aware 5.0 ± 3.3 10.8 ± 3.8 4.0 ± 2.4 13.8 ± 3.7 4.0 ± 2.7 13.1 ± 3.6 4.6 ± 2.9 12.4 ± 3.2
 Cognit 2.6 ± 2.2 16.2 ± 5.1 2.5 ± 2.3 16.2 ± 7.2 3.5 ± 3.8 14.7 ± 6.0 3.0 ± 2.0 17.4 ± 6.5
 Comm 6.6 ± 6.8 28.4 ± 11.0 4.8 ± 3.8 32.1 ± 10.6 6.4 ± 5.5 32.8 ± 11.0 7.0 ± 5.1 37.0 ± 12.9
 Motiva 3.9 ± 3.3 13.0 ± 5.6 3.4 ± 2.6 13.6 ± 7.9 3.9 ± 3.3 14.8 ± 5.8 4.6 ± 5.1 19.1 ± 8.1
 Manner 2.0 ± 3.4 15.4 ± 6.0 1.7 ± 1.7 17.9 ± 7.5 2.3 ± 3.1 20.0 ± 5.7 2.4 ± 2.9 22.4 ± 6.9
  1. Abbreviations: GU, Georgetown University; KKI, Kennedy Krieger Institute; OHSU, Oregon Health and Science University; PITT, University of Pittsburgh School of Medicine; TRINITY, Trinity Centre for Health Sciences; UCLA, University of California, Los Angeles; USM, University of Utah School of Medicine; HC, healthy control; ASD, autism spectrum disorder; N, number; A, autism type; AS, Asperger syndrome type; P, pervasive developmental disorder type; NA, not applicable; ADOS, autism diagnostic observation schedule; IQ, intelligence quotient; FIQ, full-scale IQ; VIQ, verbal IQ; PIQ, performance IQ; Comm, communication, RRB, stereotyped behaviors and restricted interests; ADOS Total = social + communication; ADI-R, autism diagnostic interview revised; SRS, social responsiveness scale; Aware, awareness; Cognit, cognition; Motiva, motivation; Manner, mannerisms; SRS Total = awareness + cognition + communication + motivation + mannerisms