Table 1 rhGH dose in mg/kg/week and IGF-1 Z scores
From: A proof-of-concept study of growth hormone in children with Phelan–McDermid syndrome
Participant | Baseline | Week 2 | Week 4 | Week 8 | Week 12 | |
|---|---|---|---|---|---|---|
1 | IGF-1 Z score | 0.8 | – | 2.6 | 4.8 | 2.2 |
rhGH dose | 0.15 | 0.3 | 0.28 | 0.24a | – | |
2 | IGF-1 Z score | 1.0 | – | 6.0 | 5.0 | 3.9 |
rhGH dose | 0.15 | 0.28 | 0.24a | 0.16a | – | |
3 | IGF-1 Z score | 1.1 | – | 2.8 | 4.7 | 1.7 |
rhGH dose | 0.14 | 0.3 | 0.29 | 0.24a | – | |
4 | IGF-1 Z score | 0.9 | – | 4.5 | 1.8 | 2.9 |
rhGH dose | 0.16 | 0.29 | 0.21a | 0.19b | – | |
5 | IGF-1 Z score | 2.3 | – | 4.9 | 4.2 | 1.3 |
rhGH dose | 0.14 | 0.27 | 0.22a | 0.13a | – | |
6 | IGF-1 Z score | − 1.2 | – | 1.1 | 1.3 | 0.9 |
rhGH dose | 0.15 | 0.31 | 0.33 | 0.32 | – |