Skip to main content

Table 1 Descriptive data for the NF1 sample (N = 68)a

From: Delineating the autistic phenotype in children with neurofibromatosis type 1

NF1 characteristics

 

p

d (95% CI)

Age in years, M (SD)

Range

9.0 (3.4)

3.4–15.9

  

Male, N (%)

Female, N (%)

38 (55.9)

30 (44.1)

  

Familial inheritance, N (%)

28 (41.2)

  

Plexiform neurofibroma, N (%)

22 (32.8)

  

Optic pathway glioma, N (%)

11 (16.4)

  

Social risk—high, N (%)

14 (20.6)

  

Full-Scale IQ, M (SD)

84.6 (12.6)

 < .001*

− 1.22 (− 1.53, − 0.90)

Verbal Comprehension Index, M (SD)

88.1 (14.7)

 < .001*

− 0.81 (− 1.09, − 0.54)

Visual Spatial Index, M (SD)

87.8 (14.7)

 < .001*

− 0.83 (− 1.11, − 0.55)

Fluid Reasoning Index, M (SD)

88.6 (13.5)

 < .001*

− 0.85 (− 1.13, − 0.56)

Intellectual disability, N (%)

8 (11.8)

  

Word Delay, N (%)

16 (24.6)

  

Phrase Delay, N (%)

25 (39.1)

  

Sex normed T-scores, M (SD)

   

SRS-2 Total

75.3 (10.2)

 < .001*

2.47 (1.99, 2.95)

SRS-2 Social Communication/Interaction

74.3 (9.5)

 < .001*

2.55 (2.05, 3.04)

SRS-2 Restricted/Repetitive Behaviour

74.9 (13.8)

 < .001*

1.81 (1.42, 2.20)

Conners Inattention

77.4 (12.5)

 < .001*

2.09 (1.58, 2.58)

Conners Hyperactivity–Impulsivity

76.4 (14.3)

 < .001*

1.85 (1.38, 2.31)

CBCL Anxiety Problems

63.2 (10.1)

 < .001*

1.20 (0.80, 1.60)

CBCL Affective Problems

66.3 (8.9)

 < .001*

1.36 (0.95, 1.75)

CBCL Oppositional Defiant Problems

60.9 (10.1)

 < .001*

0.98 (0.59, 1.37)

  1. CBCL Child Behavior Checklist, Conners Conners-Third Edition or Conners ADHD DSM-IV
  2. Rating Scale, d Cohen’s d, IQ intelligence quotient, M mean, CI confidence interval, SD standard
  3. deviation, SRS-2 Social Responsiveness Scale-Second Edition
  4. aN ranges between 64 and 68
  5. *Indicates significant difference from population norms after FDR corrections