From: Delineating the autistic phenotype in children with neurofibromatosis type 1
NF1 characteristics | Â | p | d (95% CI) |
---|---|---|---|
Age in years, M (SD) Range | 9.0 (3.4) 3.4–15.9 |  |  |
Male, N (%) Female, N (%) | 38 (55.9) 30 (44.1) | Â | Â |
Familial inheritance, N (%) | 28 (41.2) | Â | Â |
Plexiform neurofibroma, N (%) | 22 (32.8) | Â | Â |
Optic pathway glioma, N (%) | 11 (16.4) | Â | Â |
Social risk—high, N (%) | 14 (20.6) |  |  |
Full-Scale IQ, M (SD) | 84.6 (12.6) |  < .001* | − 1.22 (− 1.53, − 0.90) |
Verbal Comprehension Index, M (SD) | 88.1 (14.7) |  < .001* | − 0.81 (− 1.09, − 0.54) |
Visual Spatial Index, M (SD) | 87.8 (14.7) |  < .001* | − 0.83 (− 1.11, − 0.55) |
Fluid Reasoning Index, M (SD) | 88.6 (13.5) |  < .001* | − 0.85 (− 1.13, − 0.56) |
Intellectual disability, N (%) | 8 (11.8) | Â | Â |
Word Delay, N (%) | 16 (24.6) | Â | Â |
Phrase Delay, N (%) | 25 (39.1) | Â | Â |
Sex normed T-scores, M (SD) | Â | Â | Â |
SRS-2 Total | 75.3 (10.2) |  < .001* | 2.47 (1.99, 2.95) |
SRS-2 Social Communication/Interaction | 74.3 (9.5) |  < .001* | 2.55 (2.05, 3.04) |
SRS-2 Restricted/Repetitive Behaviour | 74.9 (13.8) |  < .001* | 1.81 (1.42, 2.20) |
Conners Inattention | 77.4 (12.5) |  < .001* | 2.09 (1.58, 2.58) |
Conners Hyperactivity–Impulsivity | 76.4 (14.3) |  < .001* | 1.85 (1.38, 2.31) |
CBCL Anxiety Problems | 63.2 (10.1) |  < .001* | 1.20 (0.80, 1.60) |
CBCL Affective Problems | 66.3 (8.9) |  < .001* | 1.36 (0.95, 1.75) |
CBCL Oppositional Defiant Problems | 60.9 (10.1) |  < .001* | 0.98 (0.59, 1.37) |