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Table 2 Demographic characteristics of study participants

From: Neurite orientation dispersion and density imaging reveals white matter microstructural alterations in adults with autism

 

Autism (N = 26)

TD (N = 25)

P-value

Age (mean ± SD, range; years)

32.93 ± 9.24, 19.29−52.93

34.43 ± 9.02, 20.45−49.21

0.56

Sex (male/female)

19/7

17/8

0.69

Years of education (mean ± SD, range)

14.67 ± 2.28, 12−19

15.32 ± 2.36, 12−19

0.33

Clinical scores:

   

AQ (mean ± SD, range)

   

 Total

32.92 ± 5.19, 22−41

15.16 ± 5.41, 5−26

 < 0.0001

 Social skill

6.96 ± 1.61, 3−9

2.40 ± 2.02, 0−8

 < 0.0001

 Attention switching

7.27 ± 1.82, 3−10

3.28 ± 1.90, 0−7

 < 0.0001

 Attention to detail

4.96 ± 1.93, 2−9

4.28 ± 2.13, 0−8

0.24

 Communication

7.31 ± 1.83, 3−10

2.00 ± 1.80, 0−6

 < 0.0001

 Imagination

6.42 ± 1.60, 4−9

3.20 ± 1.58, 1−7

 < 0.0001

 EQ (mean ± SD, range)

24.50 ± 7.42, 11−35

38.56 ± 10.76, 23−60

 < 0.0001

 SQ (mean ± SD, range)

26.73 ± 14.32, 5−59

22.40 ± 9.76, 1−47

0.22

Global brain volumes

   

 ICV (mean ± SD; mL)

1415.94 ± 218.66

1318.14 ± 258.43

0.15

 Normalized WM volume (WM volume /ICV)

0.34 ± 0.04

0.36 ± 0.05

0.09

 Normalized GM volume (GM volume/ICV)

0.44 ± 0.06

0.48 ± 0.06

0.08

  1. AQ, autism-spectrum quotient; EQ, empathy quotient; GM, gray matter; SD, standard deviation; SQ, systemizing quotient; TD, typically developing subjects; WM, white matter
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Molecular Autism

ISSN: 2040-2392