Skip to main content

Table 2 Demographic characteristics of study participants

From: Neurite orientation dispersion and density imaging reveals white matter microstructural alterations in adults with autism

  Autism (N = 26) TD (N = 25) P-value
Age (mean ± SD, range; years) 32.93 ± 9.24, 19.29−52.93 34.43 ± 9.02, 20.45−49.21 0.56
Sex (male/female) 19/7 17/8 0.69
Years of education (mean ± SD, range) 14.67 ± 2.28, 12−19 15.32 ± 2.36, 12−19 0.33
Clinical scores:    
AQ (mean ± SD, range)    
 Total 32.92 ± 5.19, 22−41 15.16 ± 5.41, 5−26  < 0.0001
 Social skill 6.96 ± 1.61, 3−9 2.40 ± 2.02, 0−8  < 0.0001
 Attention switching 7.27 ± 1.82, 3−10 3.28 ± 1.90, 0−7  < 0.0001
 Attention to detail 4.96 ± 1.93, 2−9 4.28 ± 2.13, 0−8 0.24
 Communication 7.31 ± 1.83, 3−10 2.00 ± 1.80, 0−6  < 0.0001
 Imagination 6.42 ± 1.60, 4−9 3.20 ± 1.58, 1−7  < 0.0001
 EQ (mean ± SD, range) 24.50 ± 7.42, 11−35 38.56 ± 10.76, 23−60  < 0.0001
 SQ (mean ± SD, range) 26.73 ± 14.32, 5−59 22.40 ± 9.76, 1−47 0.22
Global brain volumes    
 ICV (mean ± SD; mL) 1415.94 ± 218.66 1318.14 ± 258.43 0.15
 Normalized WM volume (WM volume /ICV) 0.34 ± 0.04 0.36 ± 0.05 0.09
 Normalized GM volume (GM volume/ICV) 0.44 ± 0.06 0.48 ± 0.06 0.08
  1. AQ, autism-spectrum quotient; EQ, empathy quotient; GM, gray matter; SD, standard deviation; SQ, systemizing quotient; TD, typically developing subjects; WM, white matter