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Table 1 The anatomical definition and functions of white matter tracts frequently involved in autism

From: Neurite orientation dispersion and density imaging reveals white matter microstructural alterations in adults with autism

White matter tracts Category Connection Function related to autism
ATR Projection fiber Dorsomedial thalamic nucleus to prefrontal cortex through the anterior limb of internal capsule Executive function and planning complex behaviors
Corpus callosum Commissural fiber The cortices of the two cerebral hemispheres Cognitive and social function
Cingulum Long-range associative fiber Cingulate gyrus to the anterior thalamic nuclei Visuospatial processing and memory access
IFOF Long-range associative fiber Occipital cortex, temporo-basal areas, and superior parietal lobe to the frontal lobe Semantic processing
ILF Long-range associative fiber Occipital lobe to the anterior temporal lobe Face and emotion recognition
SLF Long-range associative fiber Frontal lobe to parietal lobe and partially to temporal lobe Visuospatial attention, language auditory comprehension, articulatory processing, reading, and lexical access
UF Long-range associative fiber Lateral orbitofrontal cortex and Broadmann area 10 to anterior temporal lobes Episodic memory, language, and social emotional processing
  1. ATR, anterior thalamic radiation; IFOF, inferior fronto- occipital fasciculus; ILF, inferior longitudinal fasciculus; SLF, superior longitudinal fasciculus; UF, uncinate fasciculus