Maternal steroid levels and the autistic traits of the mother and infant

Table 3 Multiple regression models for predicting Q-CHAT scores and accounting for a hormone-by-sex interaction, further controlled for maternal AQ, a diagnosis of PCOS, maternal age, birth weight and infant age at Q-CHAT assessment-adjusted for gestational age at birth

	Q-CHAT
	Regression coefficient	SE	Semipartial correlation coefficient	p value
Estradiol
MR: intercept	Beta = 114.20	35.21		p = 0.002**
Hormone	Beta = −4.00	2.311	− 0.19	p = 0.087
Hormone-by-sex	Beta = 8.27	4.08	0.23	p = 0.036*
Testosterone
MR: intercept	Beta = 80.01	29.07		p = 0.007**
Hormone	Beta = −1.95	2.12	− 0.10	p = 0.362
Hormone-by-sex	Beta = 0.99	3.28	0.03	p = 0.765
DHEAS
MR: intercept	Beta = 90.03	29.68		p = 0.003**
Hormone	Beta = −2.33	1.58	− 0.16	p = 0.144
Hormone-by-sex	Beta = 1.36	3.22	0.04	p = 0.674
Progesterone
MR : intercept	Beta = 84.06	32.16		p = 0.011*
Hormone	Beta = −3.70	4.65	− 0.08	p = 0.429
Hormone-by-sex	Beta = 11.64	6.86	0.18	p = 0.095
hCG MoM
MR: intercept	Beta = 34.2	20.61		p = 0.100
Hormone	Beta = 2.95	1.07	0.24	p= 0.007**
Hormone-by-sex	Beta = −4.34	1.53	− 0.25	p = 0.005**
PAPP-A MoM
MR: intercept	Beta = 46.04	21.13		p = 0.031*
Hormone	Beta = 1.69	1.45	0.11	p = 0.245
Hormone-by-sex	Beta = −1.37	2.29	− 0.05	p = 0.552
*Composite measures*
Free Estradiol Index
MR: intercept	Beta = 82.42	29.02		p = 0.006**
Hormone	Beta = −0.969	1.37	− 0.07	p = 0.481
Hormone-by-sex	Beta = 1.989	1.68	0.13	p = 0.240
Free Testosterone Index
MR: intercept	Beta = 77.86	29.16		p = 0.009**
Hormone	Beta = 2.50	8.78	r = 0.03	p = 0.777
Hormone-by-sex	Beta = −9.53	11.69	r = −0.09	p = 0.417
Steroid factor
MR: intercept	Beta = 85.95	29.01		p = 0.004**
Hormone	Beta = −1.95	1.20	r = −0.17	p = 0.108
Hormone-by-sex	Beta = 2.80	1.81	r = 0.16	p = 0.126

ISSN: 2040-2392