Table 9 Mean biomarker gene expression at 15Â weeks of exposure to sulforaphane by presence or absence of fever effect (natural log transformed values for change from baseline)
|  | Fever effect N | Fever effect Mean (95% CI) | No fever effect N | No fever effect Mean (95% CI) | p value†|
|---|---|---|---|---|---|
NQO1 | 16 | 0.33 (− 0.34, 1.00) | 20 | 0.93 (0.26, 1.60) | 0.196 |
xCT | 17 | − 0.24 (− 0.72, 0.23) | 21 | 0.51 (0.02, 0.99) | 0.027 |
HO-1 | 17 | − 0.45 (− 1.08, 0.18) | 21 | − 0.40 (− 1.07, 0.28) | 0.906 |
HSP70 | 17 | 0.02 (− 0.22, 0.26) | 21 | − 0.35 (− 0.60, − 0.09) | 0.037 |
HSP27 | 17 | − 0.52 (− 1.12, 0.08) | 21 | − 0.70 (− 1.42, 0.02) | 0.697 |
IL-6 | 17 | − 1.59 (− 2.21, − 0.98) | 20 | − 0.98 (− 1.69, − 0.27) | 0.187 |
IL-1β | 16 | − 0.61 (− 1.27, 0.06) | 20 | − 1.12 (− 2.22, − 0.02) | 0.434 |
COX-2 | 17 | 0.08 (− 0.26, 0.41) | 21 | − 0.36 (− 0.55, − 0.18) | 0.015 |
TNF-α | 17 | − 0.30 (− 0.68, 0.07) | 21 | − 0.89 (− 1.32, − 0.46) | 0.043 |