Fig. 1

macaque Social Responsiveness Scale-Revised (mSRS-R) scores and cerebrospinal fluid (CSF) arginine vasopressin (AVP) concentration in male rhesus macaques from the general population. a mSRS-R scores are plotted as a histogram (N = 76), with higher scores indicating greater social impairment. Total mSRS-R scores could range from 17 to 119. A corresponding box-and-whisker plot is shown above the histogram. The box shows the inter-quartile range, the line the median, the whiskers the 10th and 90th percentiles, and the black circles any data out of this range. b CSF AVP concentration negatively predicts mSRS-R score (n = 57), such that individuals with the lowest CSF AVP concentration demonstrate the greatest social impairment. The observed mSRS-R score is plotted against the partialled CSF AVP concentration. Thus, CSF AVP concentration is corrected (partialled) for the other variables in the analysis and scaled to the range of the original CSF AVP concentration data