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Fig. 6 | Molecular Autism

Fig. 6

From: Tactile cortical responses and association with tactile reactivity in young children on the autism spectrum

Fig. 6

SEPs for children with and without tactile reactivity, independent of diagnosis. Grand-averaged SEP traces in response to passive tactile stimulation from ROIs over the contralateral somatosensory cortex (a) and frontal cortex (b) for the tactile typical (TT, light blue) and tactile reactive (TR, purple) groups, independent of diagnosis, for the 1050 ms ISI. Major SEP responses are clearly distinguishable: P50 (30–55 ms), N80 (55–80 ms), P100 (80–125 ms), N140 (150 –210 ms), P300 (270–350 ms) over somatosensory cortex as well as P190 (150–240 ms) and N300 (280–400 ms) over bilateral frontal cortex. Dashed line at time 0 ms indicates time of fingertip stimulation. c, Average latency and amplitude of SEP responses for children with and without tactile reactivity. Error bars indicate between-participant SEM. * differences between tactile typical (TT) and tactile reactive (TR) groups at p < 0.05 uncorrected that do not survive multiple comparison correction

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