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Fig. 3 | Molecular Autism

Fig. 3

From: A profile and review of findings from the Early Markers for Autism study: unique contributions from a population-based case–control study in California

Fig. 3

Summary of genetic findings in EMA. CNV, copy number variation; PCB, polychlorinated biphenyl; PBDE, polybrominated diphenyl ether. Further information on relationships summarized in the Figure is as follows: PBDEs associated with maternal and fetal SNP heritability: BB-153, BDE-47, BDE-100, BDE-153, Sum PBDE; cytokines associated with maternal and fetal SNP heritability: IL-4, IL-7, CXCL10, CCL1, CCL3, CCL17, CCL19, CCL22, CCL25, CXCL5; maternal metabolism loci associated with PBDEs and PCBs: CYP2B6, between ADAMTSL1 and SH3GL2; maternal cytokine loci associated with maternal cytokines: THRB/RARB, IL2R, near SMAD1; fetal non-cytokine loci associated with maternal cytokines: ADCYAP1; maternal non-cytokine loci associated with neonatal cytokines: CYP3A4, MCTP2, near EFNA5; fetal cytokine loci associated with neonatal cytokines: PLCL2, CCL23, CCL15, CXCL9/10/11, CXCL6, CCL24, ACKR4, ACKR2, FBXO25/TDRP, lincRNA

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