Table 6 Clinical summary of elevated and equivocal risk for each type of sleep disorder in each syndrome
From: Sleep disorders in rare genetic syndromes: a meta-analysis of prevalence and profile
Syndrome | Sleep-related breathing difficulties | Insomnia | Excessive daytime sleepiness | Sleep Enuresis | Sleep bruxism |
|---|---|---|---|---|---|
Angelman | + | ++ | + | ++ | + |
CHARGE | ++ | – | – | – | – |
Cornelia de Lange | ++ | ++ | + | – | – |
Cri du Chat | – | – | – | – | – |
Down | ++ | ++ | + | + | ++ |
Fragile X | ++ | + | + | ++ | ++ |
Hurler | ++ | – | – | – | – |
Jacobsen | – | – | – | – | – |
Juvenile Neuronal Ceroid Lipofuscinosis | – | – | – | – | – |
Mucopolysaccharidosis Type II | ++ | – | – | – | – |
Mucopolysaccharidosis Type IIIB | + | – | – | – | – |
Mucopolysaccharidosis Type IVA | ++ | – | – | – | – |
Neurofibromatosis | + | ++ | ++ | – | – |
Prader–Willi | ++ | + | + | + | – |
Rett | + | ++ | + | – | + |
Smith–Magenis | – | + | ++ | – | – |
Smith–Lemli–Opitz | – | – | – | – | – |
Tuberous Sclerosis Complex | – | ++ | ++ | – | – |
Williams | ++ | ++ | + | + | + |