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Table 1 Subjects characteristics

From: Modulation of atypical brain activation during executive functioning in autism: a pharmacological MRI study of tianeptine

 

ASD (n = 19)

TD (n = 19)

t-test p value

Age

30 ± 11 (19–50)

27 ± 9 (19–52)

0.3

IQ

113 ± 14 (79–139)

115 ± 10 (88–130)

0.7

ADI-R—Communication

17 ± 9

–

 

ADI-R—Social Interaction

14 ± 8

–

 

ADI-R—Repetitive Behaviour

5 ± 2

–

 

ADOS—Communication

3 ± 2

–

 

ADOS—Social Interaction

6 ± 2

–

 

AQ

31 ± 11

12 ± 7

 < 0.001***

HAM-D

6 ± 4

2 ± 3

0.001**

HAM-A

8 ± 6

3 ± 4

0.003**

OCI-R

23 ± 13

8 ± 9

 < 0.001***

GAD-7

7 ± 5

3 ± 3

0.01*

Barkley Inattention Childhood Self

3.3 ± 3.0

0.7 ± 1.2

0.002**

Barkley Hyperactivity Childhood Self

3.7 ± 2.9

1.1 ± 1.9

0.004**

Barkley Inattention Currently Self

1.4 ± 1.8

0.7 ± 1.5

0.2

Barkley Hyperactivity Currently Self

1.2 ± 1.3

0.4 ± 0.8

0.004**

  1. Data in table are shown as mean ± standard deviation (range) (n = number of participants). n = 19 for sustained attention task and n = 17 for Go/No-Go task, which did not significantly affect between-group differences in baseline characteristics or visual analogue scale measures
  2. TD typically developed controls, ASD individuals with autism spectrum disorder, ADOS Autism Diagnostic Observation Scale, ADI-R Autism Diagnostic Interview-Revised, AQ Autism Quotient, HAM-D Hamilton Depression Rating Scale, HAM-A Hamilton Anxiety Rating Scale, OCI-R Obsessive–Compulsive Inventory Revised, GAD-7 Generalized Anxiety Disorder Assessment
  3. Between group t-test: *p < 0.05; **p < 0.01; ***p < 0.001
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Molecular Autism

ISSN: 2040-2392