Fig. 3

Elevation in delta power is persistent across light and dark cycles in Ube3a-del mice. Power spectral densities across all frequency bands were analyzed by light–dark cycles as well as delta power, relative delta power and total power between genotype. a Power spectral density collected from Ube3a-del mice during the light cycle differed from WT, specifically in the delta frequency range where Ube3a-del mice had higher delta power. e Trends toward elevated power spectral densities were also observed in Ube3a-del mice during the dark cycle. Quantification of b, f delta power and c, g relative delta power was significantly increased in Ube3a-del mice compared to WT littermate controls across light and dark cycles. d, h Total power was higher in Ube3a-del animals during the light cycle, with trends toward significance during the dark cycle (p = 0.125), due to their elevated delta power. *p < 0.05, Two-way RM ANOVA comparing genotypes across frequency and Student’s t test between genotype