Fig. 1

Overlap across R-fMRI metrics for main effects of diagnosis and sex. Upper panel: the surface inflated maps depict the extent of overlap across clusters showing significant main effects of diagnosis (left) and sex (right) across any of three resting state fMRI (R-fMRI) metrics showing statistically significant effects (Z > 3.1, P < 0.01). Purple clusters represent areas of significant group differences emerging for only one of any of the three R-fMRI measures, orange and yellow clusters indicate measures with overlap among 2 and 3 R-fMRI measures (see Additional file 1: Figure S2 for statistical maps of main effects for each R-fMRI metric). Cluster masks are overlaid on inflated brain maps generated by BrainNet Viewer. Lower panel: For each of the yellow and orange clusters in panel A, the table lists the cluster’s anatomical label based on the Harvard Oxford atlas, the specific R-fMRI metrics involved, and the group difference direction (ASD < NT or M < F in blue, ASD > NT or M > F in red). L left hemisphere, R right hemisphere, PCG/FP paracingulate cortex/frontal pole, ACC anterior cingulate cortex, PCC/Prec posterior cingulate cortex/precuneus, ASD autism spectrum disorder, NT neurotypical, M males, F females