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Fig. 2 | Molecular Autism

Fig. 2

From: Behavioral effects of multiple-dose oxytocin treatment in autism: a randomized, placebo-controlled trial with long-term follow-up

Fig. 2

Effects of oxytocin treatment on autism symptoms and attachment. Mean pre-to-post changes (change from baseline) on self-report and informant-based questionnaires are visualized for the oxytocin (OT) and placebo (PL) treatment groups at assessment session “T1” (immediately after the four-week treatment), “T2” (at follow-up, one month post-treatment), and “T3” (at follow-up, 1 year post-treatment). Mean changes from baseline are visualized separately for a Social Responsiveness Scale (SRS-A) self-report version, b SRS-A informant-based version, c Repetitive Behavior Scale-Revised (RBS-R), d State Adult Attachment Measure (SAAM) Avoidance subscale, e SAAM Security subscale, and f SAAM Anxiety subscale. Lower scores indicate improvement for the SRS-A, RBS-R, SAAM Avoidance, and SAAM Anxiety questionnaires. For the SAAM Security questionnaire, higher scores indicate improvement. Vertical bars denote ± standard errors. Asterisks (*) indicate Cohen’s d ≥ .50 (medium-sized effect). Circles (°) indicate Cohen’s d ≥ .80 (large-sized effect)

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