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Table 4 Comparing PAC metrics across categorical phenotypes in Phelan-McDermid Syndrome

From: Shifted phase of EEG cross-frequency coupling in individuals with Phelan-McDermid syndrome

Measure PAC median Mann–Whitney U P value
z-MI
 Sex
  Female 2.99 (1.19, 9.83) 2.16 .031
  Male 0.836 (0.512, 1.485)
 ASD diagnosis
  Yes 1.45 (0.337, 3.73) -.712 .501
  No 1.60 (0.907, 6.71)
 SHANK3
  Deletion 1.22 (0.559, 4.98) − .723 .497
  Mutation 1.59 (1.23, 9.63)
 Seizure history
  Yes 1.84 (.086, 9.50) .371 .748
  No 1.23 (.626, 4.35)
Phase bias * 104
 Sex
  Female 5.00 (2.29, 15.7) 1.00 .336
  Male 3.67 (− 0.007, 5.17)
 ASD diagnosis
  Yes 4.28 (2.88, 15.5) .876 .403
  No 3.33 (.534, 7.85)
 SHANK3
  Deletion 4.14 (0.210, 15.7) .145 .910
  Mutation 4.04 (0.751, 7.57)
 Seizure history
  Yes 7.99 (− 1.85, 18.5) .889 .409
  No 3.84 (1.42, 6.71)
  1. Median values (25th and 75th percentile values in parentheses) are presented for each category. All tests performed using a Mann–Whitney U test. A Benjamini–Hochberg correction was applied to ln(z-MI) and phase bias comparisons separately. * indicates significance (FDR = .1)