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Table 2 Brain volume differences relative to control wildtype littermates

From: Distinct, dosage-sensitive requirements for the autism-associated factor CHD8 during cortical development

Brain area Chd8 genotype
+/− (%) neo/neo (%)
Brain volume 2.73 4.53**
Cortex 3.82 5.53**
Cerebellum 3.41 6.99**
Hippocampus 5.97 5.84**
Primary motor cortex 3.68 6.68**
Primary somatosensory cortex 3.7 5.62**
Primary auditory cortex 3.2 6.23**
Primary visual cortex 3.39 7.15**
Frontal cortex 3.99 5.21**
Frontal association cortex 4.81 6.07**
Entorhinal cortex 4.83 7.05**
Cingulate cortex 4.57 4.84**
Amygdala 3.82 4.64*
  1. FDR < 0.15; *FDR < 0.05; **FDR < 0.01. MRI data from Chd8+/− and littermate control mice used for comparison are from Suetterlin et al. [18]