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Fig. 2 | Molecular Autism

Fig. 2

From: Analysis of common genetic variation and rare CNVs in the Australian Autism Biobank

Fig. 2

PGS results: Mean PGS ± 95% CI for the ASD, SIB and UNR groups for a ASD, and b IQ (Additional file 2: Table 3). Scatterplots illustrating correlation between the following pairs of traits, with coefficient and p-value in the bottom right corner of each panel for the single combined analysis: c IQ PGS and measured IQ (WASI) in parents with fathers in red and mothers in green (overall r = 0.17, 8.0e−7); d IQ PGS and measured IQ (WISC fsiq composite) in the AAB ASD group with IQ < 70 (red), ASD group with IQ ≥ 70 (green), SIB group (blue) and UNR group (purple), (overall r = 0.1, p = 4.0e−2); e IQ PGS and measured IQ (WISC fsiq composite) in the SIB (red) and UNR (green) groups (overall r = 0.24, p = 2.1e−3); (f) chronotype PGS and Children’s Sleep Habits Questionnaire in the ASD (red), SIB (green) and UNR (blue) groups (overall r = 0.06, p = 7.7e−2). The correlation coefficient for the ASD subset in red is r = 0.13, p = 1.9e−3)

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