Fig. 1
From: Analysis of common genetic variation and rare CNVs in the Australian Autism Biobank
Characteristics of the AAB dataset. a Diagram showing cohort relationships. b Counts of familial relationships, split by ancestry. Ancestry is assigned to a family if the entire family is of the same genetic ancestry. N: total number of individuals in each ancestry group. Families: the number of families with both parents and at least one child. Subsequent rows (“n = ”) demonstrate the breakdown by family size (e.g., n = 3 denotes trios, n = 4 denotes quartets, and so on). The numbers in brackets refer to the number of families with one child on the autistic spectrum versus the number of families with multiple children on the autistic spectrum. c) Genetic ancestry of AAB individuals projected onto the first two principal components of the 1000 Genomes reference dataset. Pink denotes the AAB group. Acronyms for ancestry groups: AFR, African; AMR, American (Central and South) ; EAS, East Asian; EUR, European; SAS, South Asian. d) Overview of analyses performed, divided into common SNP analyses (upper) and rare copy-number variation analyses (lower). The number of tests used to calculate Bonferroni correction are also displayed