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Fig. 1 | Molecular Autism

Fig. 1

From: Targeting the RHOA pathway improves learning and memory in adult Kctd13 and 16p11.2 deletion mouse models

Fig. 1

Outline of the behavioral pipeline used for investigating the therapeutic effects of the drug fasudil in the Kctd13+/− and 16p11.2 Del/+ mouse models. We used 3 independent subcohorts of animals for each mouse line. 12-week-old mice were subjected to different behavior and learning tests, after prior habituation to the phenotyping zone. At 14 weeks, each cohort was divided into two groups. The first group started the fasudil treatment and the second group followed the cognitive characterization without treatment. NOL novel object location, NOR novel object recognition

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