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Table 1 Demographic and behavioural characteristics

From: Gene functional networks and autism spectrum characteristics in young people with intellectual disability: a dimensional phenotyping study

  Chromatin (N = 23) Synaptic (N = 29) t-test
Mean (SD) Range Mean (SD) Range Chromatin–synaptic
Gender 11F:12M 19F:10M
Age 12.93 (5.14) 5 to 25 15.38 (5.23) 7 to 26 t(50) = − 1.69
p = 0.097
d = 0.47
Vineland composite 64.96 (11.90) 41 to 96 49.59 (13.97) 20 to 79 t(50) = 4.20
p < 0.001
d = 1.18
SRS total (T) 76.30 (12.73) 53 to 96 75.52 (11.30) 49 to 98 t(50) = 0.24
p = 0.814
d = 0.06
SRS raw score > 60 (clinical significance) 19/23 (82.60%) 26/29 (89.66%)
CPRS inattention (T)a 79.71 (11.49) 60 to 90 80.50 (10.99) 55 to 90 t(43) = − 0.23
p = 0.816
d = 0.07
CPRS hyperactivity (T)a 69.05 (14.55) 40 to 90 76.92 (15.03) 42 to 90 t(43) = − 1.78
p = 0.082
d = 0.53
DBC total (percentile) 61.65 (28.59) 2 to 100 67.93 (26.49) 18 to 98 t(50) = − 0.82
p = 0.416
d = 0.23
DBC anxiety (percentile) 55.39 (28.09) 10 to 98 56.55 (25.51) 10 to 98 t(50) = − 0.16
p = 0.877
d = 0.04
Factor 1 (Inflexibility)b 0.23 (1.06)  − 1.52 to 2.20  − 0.18 (0.93)  − 1.89 to 1.58 t(50) = − 1.49
p = 0.143
d = 0.41
Factor 2 (Social understanding)b  − 0.17 (1.13)  − 2.39 to 1.90 0.13 (0.88)  − 2.13 to 1.45 t(50) = − 1.09
p = 0.280
d = 0.30
Factor 3 (Social motivation)b  − 0.03 (1.11)  − 1.67 to 2.03 0.02 (0.92)  − 1.42 to 1.71 t(50) = − 0.167
p = 0.868
d = 0.05
  1. a45 of 52 participants (21 in the chromatin group and 24 in the synaptic group) completed the CPRS
  2. bFactor scores were transformed to z-scores, with a mean of 0 and standard deviation of 1