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Table 1 Demographic and behavioural characteristics

From: Gene functional networks and autism spectrum characteristics in young people with intellectual disability: a dimensional phenotyping study

 

Chromatin (N = 23)

Synaptic (N = 29)

t-test

Mean (SD)

Range

Mean (SD)

Range

Chromatin–synaptic

Gender

11F:12M

19F:10M

Age

12.93 (5.14)

5 to 25

15.38 (5.23)

7 to 26

t(50) = − 1.69

p = 0.097

d = 0.47

Vineland composite

64.96 (11.90)

41 to 96

49.59 (13.97)

20 to 79

t(50) = 4.20

p < 0.001

d = 1.18

SRS total (T)

76.30 (12.73)

53 to 96

75.52 (11.30)

49 to 98

t(50) = 0.24

p = 0.814

d = 0.06

SRS raw score > 60 (clinical significance)

19/23 (82.60%)

26/29 (89.66%)

CPRS inattention (T)a

79.71 (11.49)

60 to 90

80.50 (10.99)

55 to 90

t(43) = − 0.23

p = 0.816

d = 0.07

CPRS hyperactivity (T)a

69.05 (14.55)

40 to 90

76.92 (15.03)

42 to 90

t(43) = − 1.78

p = 0.082

d = 0.53

DBC total (percentile)

61.65 (28.59)

2 to 100

67.93 (26.49)

18 to 98

t(50) = − 0.82

p = 0.416

d = 0.23

DBC anxiety (percentile)

55.39 (28.09)

10 to 98

56.55 (25.51)

10 to 98

t(50) = − 0.16

p = 0.877

d = 0.04

Factor 1 (Inflexibility)b

0.23 (1.06)

 − 1.52 to 2.20

 − 0.18 (0.93)

 − 1.89 to 1.58

t(50) = − 1.49

p = 0.143

d = 0.41

Factor 2 (Social understanding)b

 − 0.17 (1.13)

 − 2.39 to 1.90

0.13 (0.88)

 − 2.13 to 1.45

t(50) = − 1.09

p = 0.280

d = 0.30

Factor 3 (Social motivation)b

 − 0.03 (1.11)

 − 1.67 to 2.03

0.02 (0.92)

 − 1.42 to 1.71

t(50) = − 0.167

p = 0.868

d = 0.05

  1. a45 of 52 participants (21 in the chromatin group and 24 in the synaptic group) completed the CPRS
  2. bFactor scores were transformed to z-scores, with a mean of 0 and standard deviation of 1