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Table 3 Summary of genome-wide associations of molecular profiles with SRS and IQ at FDR-adjusted \(P < 0.01\)

From: Evidence for the placenta-brain axis: multi-omic kernel aggregation predicts intellectual and social impairment in children born extremely preterm

Biomarker

Effect size

FDR-adjusted

\({P }\)value

SRS

  

mRNA expression

  

 HECA

0.571

0.001

 LMO4

0.467

0.001

IQ

Biomarker

  

 mRNA expression

  

 RAB5A

 − 0.516

0.002

 TMEM167A

 − 0.632

0.004

 ITPRIPL2

 − 0.557

0.004

 STAT2

 − 0.584

0.004

CpG methylation site

  

 cg09418354 (within CHST11)

 − 0.005

0.002

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Molecular Autism

ISSN: 2040-2392