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Table 1 Study characteristics by sex of the child

From: Meconium androgens are correlated with ASD-related phenotypic traits in early childhood in a familial enriched risk cohort

Characteristic Total Female Male P
Mean SD Mean SD Mean SD  
Maternal age 34.5 4.5 34.4 4.5 34.6 4.5 0.84
Gestational age at delivery (weeks) 39.3 1.7 39.3 1.8 39.3 1.5 0.96
Interpregnancy interval (days) 1671 968 1737 880 1617 1038 0.47
Total number of pregnancies 3.7 1.6 3.5 1.4 3.9 1.7 0.16
Androgen levels        
 ln(u-T) -1.2 2.1 -1.7 2.0 -0.8 2.1 0.0083
 ln(t-T) 3.1 1.6 2.8 1.6 3.4 1.5 0.018
 ln(u-A4) 2.9 0.6 2.9 0.6 2.8 0.5 0.30
 ln(t-A4) 5.3 0.6 5.4 0.7 5.2 0.5 0.17
 ln(u-DHEA) 2.4 0.8 2.5 0.8 2.3 0.7 0.051
 ln(t-DHEA) 7.2 1.3 7.2 1.4 7.2 1.3 0.71
Outcome scores        
 Total AOSI scorea 5.2 2.1 4.9 1.9 5.4 2.2 0.46
 Total SRS scorea 28.4 2.0 22.4 1.7 34.4 2.0 < 0.0001
  Mean (median) SD (IQR) Mean (median) SD (IQR) Mean (median) SD (IQR)  
Total AOSI score 5.5 (5) 4.1 (3–8) 4.8 (4) 3.1 (3–7) 6.0 (5) 4.8 (2.5–8.5) 0.33b
Total SRS score 35.7 (28) 25.8 (18–42) 25.6 (22) 13.2 (16–33) 43.8 (35) 30.2 (21–65) < 0.001b
  % n % n % n  
Cesarean delivery        
 Yes 35.3 48 38.3 23 32.9 25 0.51
Maternal race        
 White 66.9 89 61.0 36 71.6 53 0.50
 Black 9.8 13 13.6 8 6.8 5  
 Asian 12.0 16 13.6 8 10.8 8  
 Other 11.3 15 11.9 7 10.8 8  
Maternal ethnicity        
 Hispanic 17.5 24 16.4 10 18.4 14 0.76
Maternal education        
 < 9th 3.7 5 4.9 3 2.7 2 0.94
 High school graduate 25.9 35 26.2 16 25.7 19  
 College 40.7 55 39.3 24 41.9 31  
 Graduate/professional degree 29.6 40 29.5 18 29.7 22  
Income        
 < $29,999 8.4 11 6.9 4 9.6 7 0.03
 $30,000–49,999 16.8 22 25.9 15 9.6 7  
 $50,000–74,999 15.3 20 15.5 9 15.1 11  
 $75,999–99,999 16.0 21 6.9 4 23.3 17  
 $100,000+ 43.5 57 44.8 26 42.5 31  
Sex of the proband        
 Female 16.8 23 16.4 10 17.1 13 0.91
 Male 83.2 114 83.6 51 82.9 63  
  1. aGeometric mean and geometric standard deviation
  2. bTwo-sided P value for Mann–Whitney U test