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Table 1 Study characteristics by sex of the child

From: Meconium androgens are correlated with ASD-related phenotypic traits in early childhood in a familial enriched risk cohort

Characteristic

Total

Female

Male

P

Mean

SD

Mean

SD

Mean

SD

 

Maternal age

34.5

4.5

34.4

4.5

34.6

4.5

0.84

Gestational age at delivery (weeks)

39.3

1.7

39.3

1.8

39.3

1.5

0.96

Interpregnancy interval (days)

1671

968

1737

880

1617

1038

0.47

Total number of pregnancies

3.7

1.6

3.5

1.4

3.9

1.7

0.16

Androgen levels

       

 ln(u-T)

-1.2

2.1

-1.7

2.0

-0.8

2.1

0.0083

 ln(t-T)

3.1

1.6

2.8

1.6

3.4

1.5

0.018

 ln(u-A4)

2.9

0.6

2.9

0.6

2.8

0.5

0.30

 ln(t-A4)

5.3

0.6

5.4

0.7

5.2

0.5

0.17

 ln(u-DHEA)

2.4

0.8

2.5

0.8

2.3

0.7

0.051

 ln(t-DHEA)

7.2

1.3

7.2

1.4

7.2

1.3

0.71

Outcome scores

       

 Total AOSI scorea

5.2

2.1

4.9

1.9

5.4

2.2

0.46

 Total SRS scorea

28.4

2.0

22.4

1.7

34.4

2.0

< 0.0001

 

Mean (median)

SD (IQR)

Mean (median)

SD (IQR)

Mean (median)

SD (IQR)

 

Total AOSI score

5.5 (5)

4.1 (3–8)

4.8 (4)

3.1 (3–7)

6.0 (5)

4.8 (2.5–8.5)

0.33b

Total SRS score

35.7 (28)

25.8 (18–42)

25.6 (22)

13.2 (16–33)

43.8 (35)

30.2 (21–65)

< 0.001b

 

%

n

%

n

%

n

 

Cesarean delivery

       

 Yes

35.3

48

38.3

23

32.9

25

0.51

Maternal race

       

 White

66.9

89

61.0

36

71.6

53

0.50

 Black

9.8

13

13.6

8

6.8

5

 

 Asian

12.0

16

13.6

8

10.8

8

 

 Other

11.3

15

11.9

7

10.8

8

 

Maternal ethnicity

       

 Hispanic

17.5

24

16.4

10

18.4

14

0.76

Maternal education

       

 < 9th

3.7

5

4.9

3

2.7

2

0.94

 High school graduate

25.9

35

26.2

16

25.7

19

 

 College

40.7

55

39.3

24

41.9

31

 

 Graduate/professional degree

29.6

40

29.5

18

29.7

22

 

Income

       

 < $29,999

8.4

11

6.9

4

9.6

7

0.03

 $30,000–49,999

16.8

22

25.9

15

9.6

7

 

 $50,000–74,999

15.3

20

15.5

9

15.1

11

 

 $75,999–99,999

16.0

21

6.9

4

23.3

17

 

 $100,000+

43.5

57

44.8

26

42.5

31

 

Sex of the proband

       

 Female

16.8

23

16.4

10

17.1

13

0.91

 Male

83.2

114

83.6

51

82.9

63

 
  1. aGeometric mean and geometric standard deviation
  2. bTwo-sided P value for Mann–Whitney U test