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Fig. 4 | Molecular Autism

Fig. 4

From: The eIF4E homolog 4EHP (eIF4E2) regulates hippocampal long-term depression and impacts social behavior

Fig. 4

Heterozygous deletion of Gigyf2, Eif4e2, or both in mice does not result in ASD-like behavioral deficits. a, e and i The amount of time the test mouse of the specified genotype spent sniffing either S1 or E. b, f, j The amount of time the test mouse of the specified genotype spent sniffing either S1 or S2. d, h, l The number of marbles buried by the specified genotypes in 20 min. c, g, k Distance travelled over time during the 10 min habituation phase of the three-chamber social interaction test by the specified genotypes. Data are presented as mean ± s.e.m.; *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001, NS not significant; calculated by unpaired t-test or 2-way ANOVA with Bonferroni multiple comparisons test. Sample size is located within bar graphs

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