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Fig. 2 | Molecular Autism

Fig. 2

From: Functional relationships between recessive inherited genes and genes with de novo variants in autism spectrum disorder

Fig. 2

Functional network of ASD-associated RIGs and DNGs. a Network of ASD-associated RIGs and DNGs based on PPI and co-expression in the human brain. b Comparison of the numbers of RIGs and DNGs in the functional clusters. There were 85 genes in the network and 157 genes (RIGs and DNGs) in total. *p ≤ 0.05; **p ≤ 0.01; ***p ≤ 0.001. ASD, autism spectrum disorder; RIGs, recessive inherited genes; DNGs, genes with de novo variants; PPI, protein–protein interaction

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