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Table 5 Difference in MNS activation between ASD and TD in adolescent subgroup

From: Differential mirror neuron system (MNS) activation during action observation with and without social-emotional components in autism: a meta-analysis of neuroimaging studies

Brain regions with peak activation Cluster breakdown
Anatomical region L/R Total number of voxels MNI coordinates SDM-Z p (uncorrected) Anatomical regions (Broadmann area)
ASD>TD
 Inferior frontal gyrus (orbital part) R 927 48,30, − 8 2.441 < 0.0001 Inferior frontal gyrus, orbital part (BA47)
Inferior frontal gyrus, triangular part (BA45)
 Inferior frontal gyrus (orbital part) L 484 − 44, 24, − 8 1.882 < 0.001 Inferior frontal gyrus, orbital part (BA47)
Inferior frontal gyrus, triangular part (BA47)
 Postcentral gyrus R 410 62, − 14, 34 1.659 ~0.001 Postcentral gyrus (BA3, BA43)
Precentral gyrus (BA4,BA6)
 Supramarginal gyrus L 20 − 56, − 40, 36 1.531 < 0.005 Supramarginal gyrus (BA40, BA2)
Inferior parietal gyrus (BA40)
ASD<TD
 Fusiform gyrus L 300 − 24, − 82, − 18 − 1.780 < 0.001 Fusiform gyrus (BA18, BA19)
Lingual gyrus (BA18)
 Median cingulate R 121 32, − 12, − 26 − 1.409 ~0.001 Hippocampus (BA20)
Median cingulate
 Cerebellum, hemispheric lobule VI L 56 − 38, − 62, − 26 − 1.350 < 0.005 Cerebellum, hemispheric lobule VI (BA37)
Cerebellum, crus I (BA37)