Skip to main content

Table 5 Difference in MNS activation between ASD and TD in adolescent subgroup

From: Differential mirror neuron system (MNS) activation during action observation with and without social-emotional components in autism: a meta-analysis of neuroimaging studies

Brain regions with peak activation

Cluster breakdown

Anatomical region

L/R

Total number of voxels

MNI coordinates

SDM-Z

p (uncorrected)

Anatomical regions (Broadmann area)

ASD>TD

 Inferior frontal gyrus (orbital part)

R

927

48,30, − 8

2.441

< 0.0001

Inferior frontal gyrus, orbital part (BA47)

Inferior frontal gyrus, triangular part (BA45)

 Inferior frontal gyrus (orbital part)

L

484

− 44, 24, − 8

1.882

< 0.001

Inferior frontal gyrus, orbital part (BA47)

Inferior frontal gyrus, triangular part (BA47)

 Postcentral gyrus

R

410

62, − 14, 34

1.659

~0.001

Postcentral gyrus (BA3, BA43)

Precentral gyrus (BA4,BA6)

 Supramarginal gyrus

L

20

− 56, − 40, 36

1.531

< 0.005

Supramarginal gyrus (BA40, BA2)

Inferior parietal gyrus (BA40)

ASD<TD

 Fusiform gyrus

L

300

− 24, − 82, − 18

− 1.780

< 0.001

Fusiform gyrus (BA18, BA19)

Lingual gyrus (BA18)

 Median cingulate

R

121

32, − 12, − 26

− 1.409

~0.001

Hippocampus (BA20)

Median cingulate

 Cerebellum, hemispheric lobule VI

L

56

− 38, − 62, − 26

− 1.350

< 0.005

Cerebellum, hemispheric lobule VI (BA37)

Cerebellum, crus I (BA37)