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Table 3 Difference in MNS activation between ASD and TD during observation of stimuli without social-emotional components

From: Differential mirror neuron system (MNS) activation during action observation with and without social-emotional components in autism: a meta-analysis of neuroimaging studies

Brain regions with peak activation

Cluster breakdown

Anatomical region

L/R

Total number of voxels

MNI coordinates

SDM-Z

p (uncorrected)

Anatomical regions (Broadmann area)

ASD>TD

 Inferior parietal lobule

L

1036

− 42, − 50, 48

2.382

< 0.0001

Inferior parietal lobule (BA40)

 Supplementary motor area

L

185

− 4, 4, 54

1.997

< 0.001

Supplementary motor area (BA6)

ASD<TD

 Middle occipital gyrus

R

368

32, − 84, 2

− 2.172

< 0.0005

Middle occipital gyrus (BA18)

Middle occipital gyrus (BA19)

Inferior network, inferior longitudinal fasciculus

 Postcentral gyrus

L

306

− 42, − 14, 48

− 1.950

< 0.0005

Precentral gyrus (BA6)

Postcentral gyrus (BA6)

 Postcentral gyrus

R

30

22, − 46, 60

− 1.451

< 0.005

Postcentral gyrus (BA2)

 Cerebellum, crus I

L

20

− 26, − 82, − 24

− 1.428

< 0.005

Cerebellum, crus I (BA19)