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Fig. 2 | Molecular Autism

Fig. 2

From: Autism-associated variants of neuroligin 4X impair synaptogenic activity by various molecular mechanisms

Fig. 2

Characterization of NL4X shedding. a Immunoblot analysis of overexpressed NL4X in various fibroblasts derived from Adam KO mice. b Quantification of the levels of sNL4X in the conditioned medium from Adam10 KO fibroblasts (n = 3, ***p < 0.001 vs WT by student t test). c Schematic depiction of NL4X deletion mutants analyzed in this study. d Immunoblot analysis of overexpressed NL4X mutants. Note that several mutants affected the shedding of NL4X as summarized in c

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Molecular Autism

ISSN: 2040-2392