| 22q11.nonASD | 22q11.ASD | ASD | Controls | Test statistic | |||||
---|---|---|---|---|---|---|---|---|---|---|
(n = 25 [11♂, 14♀]) | (n = 25 [13♂, 12♀]) | (n = 40 [32♂, 8♀]) | (n = 41 [23♂, 18♀]) | χ2 | p | |||||
IoPPN/UCLA/Frankfurt | 8/17/0 | 17/8/0 | 0/0/40 | 14/14/13 | 105.03 | < 0.001 | ||||
 |  |  |  |  |  |  |  |  | F | p |
Age [years] | 14 ± 6 | (6–25) | 15 ± 4 | (7–23) | 15 ± 2 | (11–18) | 14 ± 4 | (7–24) | 0.18 | 0.91 |
Full-scale IQ | 86 ± 15 | (60–116) | 81 ± 12 | (61–112) | 96 ± 13 | (64–116) | 104 ± 11 | (76–123) | 21.01 | < 0.001 |
ADI-R social1 | 5 ± 3 | (1–9) | 19 ± 5 | (9–28) | 17 ± 4 | (9–27) | n/a | n/a | 95.93 | < 0.001 |
ADI-R communication1 | 6 ± 4 | (0–16) | 14 ± 4 | (8–24) | 13 ± 4 | (5–23) | n/a | n/a | 29.98 | < 0.00 |
ADI-R repetitive1 | 1 ± 2 | (0–8) | 3 ± 3 | (0–10) | 5 ± 2 | (1–10) | n/a | n/a | 16.8 | < 0.001 |
ADOS CSS1 | 3 ± 2 | (1–8) | 6 ± 3 | (1–10) | 6 ± 3 | (1–10) | n/a | n/a | 9.3 | < 0.001 |
SRS total score | 55 ± 26 | (16–103) | 101 ± 33 | (41–174) | 95 ± 29 | (42–159) | 23 ± 19 | (0–75) | 69.38 | < 0.001 |
SRS repetitive | 9 ± 6 | (1–22) | 17 ± 7 | (7–32) | 16 ± 7 | (0–34) | 2 ± 3 | (0–10) | 49.31 | < 0.001 |
Total cortical volume [L] | 0.66 ± 0.08 | (0.41–0.89) | 0.68 ± 0.07 | (0.52–0.78) | 0.75 ± 0.07 | (0.60–0.92) | 0.73 ± 0.07 | (0.59–0.90) | 10.56 | < 0.001 |
Total surface area [m2] | 0.20 ± 0.02 | (0.13–0.25) | 0.21 ± 0.02 | (0.17–0.24) | 0.23 ± 0.02 | (0.18–0.27) | 0.22 ± 0.02 | (0.19–0.27) | 12.41 | < 0.001 |
Mean cortical thickness [mm] | 2.78 ± 0.13 | (2.59–3.06) | 2.77 ± 0.10 | (2.60–2.96) | 2.71 ± 0.10 | (2.51–2.93) | 2.71 ± 0.10 | (2.48–3.01) | 3.74 | < 0.05 |