Table 5 Main effects of IQ, Age, and Diagnosis in the Yale sample.
From: Evidence against the “normalization” prediction of the early brain overgrowth hypothesis of autism
Yale Effects of IQ, Age, and Diagnosis | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Predictors | Estimates | std. Beta | p | partial η2 | Estimates | std. Beta | p | partial η2 | Estimates | std. Beta | p | partial η2 |
TBV | GMV | WMV | ||||||||||
Intercept | 1142.35 | 0.21 | <0.001 | 0.84 | 743.62 | 0.20 | <0.001 | 0.88 | 399.25 | 0.16 | <0.001 | 0.70 |
IQ | 1.52 | 0.31 | <0.001 | 0.09 | 0.57 | 0.18 | 0.005 | 0.05 | 0.95 | 0.38 | <0.001 | 0.13 |
Age | -3.40 | -0.29 | <0.001 | 0.09 | -4.23 | -0.56 | <0.001 | 0.32 | 0.82 | 0.13 | 0.064 | 0.02 |
Diagnosis | -46.16 | -0.42 | 0.006 | 0.04 | -27.85 | -0.39 | 0.003 | 0.05 | -18.36 | -0.32 | 0.035 | 0.03 |
R2 / R2 adjusted | 0.180 / 0.166 | 0.380 / 0.369 | 0.150 / 0.135 | |||||||||
Cortical GMV | Cortical WMV | |||||||||||
Intercept | 577.03 | 0.21 | <0.001 | 0.86 | 376.56 | 0.16 | <0.001 | 0.69 | ||||
IQ | 0.40 | 0.15 | 0.019 | 0.03 | 0.89 | 0.37 | <0.001 | 0.12 | ||||
Age | -3.67 | -0.57 | <0.001 | 0.34 | 0.77 | 0.13 | 0.073 | 0.02 | ||||
Diagnosis | -24.53 | -0.41 | 0.002 | 0.06 | -16.98 | -0.31 | 0.042 | 0.02 | ||||
R2 / R2 adjusted | 0.398 / 0.387 | 0.145 / 0.130 | ||||||||||
Cerebellum | Cerebellar GMV | Cerebellar WMV | ||||||||||
Intercept | 130.65 | 0.11 | <0.001 | 0.79 | 107.96 | 0.07 | <0.001 | 0.80 | 22.69 | 0.19 | <0.001 | 0.62 |
IQ | 0.16 | 0.26 | 0.001 | 0.06 | 0.11 | 0.21 | 0.007 | 0.04 | 0.05 | 0.32 | <0.001 | 0.09 |
Age | -0.29 | -0.19 | 0.010 | 0.04 | -0.35 | -0.28 | <0.001 | 0.08 | 0.06 | 0.14 | 0.059 | 0.02 |
Diagnosis | -2.94 | -0.21 | 0.180 | 0.01 | -1.55 | -0.14 | 0.384 | 0.00 | -1.38 | -0.37 | 0.019 | 0.03 |
R2 / R2 adjusted | 0.092 / 0.076 | 0.110 / 0.094 | 0.117 / 0.102 | |||||||||
Lateral Ventricles | Third Ventricles | GMV:WMV Ratio | ||||||||||
Intercept | 9.10 | 0.27 | 0.001 | 0.06 | 0.84 | 0.21 | <0.001 | 0.30 | 1.78 | 0.02 | <0.001 | 0.92 |
IQ | 0.02 | 0.07 | 0.375 | 0.00 | -0.00 | -0.00 | 0.956 | 0.00 | -0.00 | -0.22 | <0.001 | 0.08 |
Age | 0.28 | 0.34 | <0.001 | 0.11 | 0.01 | 0.22 | 0.005 | 0.05 | -0.01 | -0.66 | <0.001 | 0.47 |
Diagnosis | -4.19 | -0.54 | <0.001 | 0.07 | -0.11 | -0.41 | 0.011 | 0.04 | -0.01 | -0.04 | 0.698 | 0.00 |
R2 / R2 adjusted | 0.148 / 0.133 | 0.070 / 0.053 | 0.529 / 0.521 | |||||||||