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Table 5 Main effects of IQ, Age, and Diagnosis in the Yale sample.

From: Evidence against the “normalization” prediction of the early brain overgrowth hypothesis of autism

Yale Effects of IQ, Age, and Diagnosis
PredictorsEstimatesstd. Betappartial η2Estimatesstd. Betappartial η2Estimatesstd. Betappartial η2
 TBVGMVWMV
Intercept1142.350.21<0.0010.84743.620.20<0.0010.88399.250.16<0.0010.70
IQ1.520.31<0.0010.090.570.180.0050.050.950.38<0.0010.13
Age-3.40-0.29<0.0010.09-4.23-0.56<0.0010.320.820.130.0640.02
Diagnosis-46.16-0.420.0060.04-27.85-0.390.0030.05-18.36-0.320.0350.03
R2 / R2 adjusted0.180 / 0.1660.380 / 0.3690.150 / 0.135
 Cortical GMVCortical WMV    
Intercept577.030.21<0.0010.86376.560.16<0.0010.69    
IQ0.400.150.0190.030.890.37<0.0010.12    
Age-3.67-0.57<0.0010.340.770.130.0730.02    
Diagnosis-24.53-0.410.0020.06-16.98-0.310.0420.02    
R2 / R2 adjusted0.398 / 0.3870.145 / 0.130    
 CerebellumCerebellar GMVCerebellar WMV
Intercept130.650.11<0.0010.79107.960.07<0.0010.8022.690.19<0.0010.62
IQ0.160.260.0010.060.110.210.0070.040.050.32<0.0010.09
Age-0.29-0.190.0100.04-0.35-0.28<0.0010.080.060.140.0590.02
Diagnosis-2.94-0.210.1800.01-1.55-0.140.3840.00-1.38-0.370.0190.03
R2 / R2 adjusted0.092 / 0.0760.110 / 0.0940.117 / 0.102
 Lateral VentriclesThird VentriclesGMV:WMV Ratio
Intercept9.100.270.0010.060.840.21<0.0010.301.780.02<0.0010.92
IQ0.020.070.3750.00-0.00-0.000.9560.00-0.00-0.22<0.0010.08
Age0.280.34<0.0010.110.010.220.0050.05-0.01-0.66<0.0010.47
Diagnosis-4.19-0.54<0.0010.07-0.11-0.410.0110.04-0.01-0.040.6980.00
R2 / R2 adjusted0.148 / 0.1330.070 / 0.0530.529 / 0.521