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Fig. 1 | Molecular Autism

Fig. 1

From: Elevated de novo protein synthesis in FMRP-deficient human neurons and its correction by metformin treatment

Fig. 1

Transcriptome profiling analysis reveals dysregulation of protein translation-related pathways in FMRP-deficient neurons. a Functional annotation of transcripts differentially expressed in FMR1KO neurons shows enrichment of protein-related synthesis pathways. b Heatmap of representative differentially expressed genes related to protein translation in neurons. c Quantitative RT-PCR analysis for validation of changes for a subset of EIF-related genes in control and FMR1KO neurons

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Molecular Autism

ISSN: 2040-2392