Table 1 Enriched GO terms for the 80 ASD-genes expressed in amygdala

Telencephalon development

2.33E−17

ARX, AVPR1A, CTNNB1, FOXP2, GRIN1, LAMB1, NF1, PAX6, PLXNA4, PTEN, RELN, SLC1A2, TBR1, TSC1

Pallium development

2.39E−14

ARX, CTNNB1, FOXP2, GRIN1, LAMB1, NF1, PAX6, PTEN, RELN, TBR1, TSC1

Forebrain neuron differentiation

1.06E−04

ARX, PAX6, TBR1

Neural crest differentiation

2.37E−07

CTNNB1, GFAP, HDAC4, SOX5, TCF4

Regulation of behavior

2.24E−11

AHI1, CNR1, CNTNAP4, HDAC4, MTOR, NRXN1, RELN

Synaptic transmission, GABAergic

1.17E−10

CNR1, CNTNAP4, GABRB2, NF1, PTEN, SLC6A1

Ionotropic glutamate receptor activity

3.10E−11

GRIA2, GRIK2, GRIK5, GRIN1, GRIN2B, NRXN1, RELN

Synaptic transmission, glutamatergic

3.89E−14

CNR1, GRIA2, GRIK2, GRIK5, GRIN1, NF1, NRXN1, PRKN, RELN

Regulation of postsynaptic membrane potential

1.77E−14

CHRNA7, GABRB2, GABRB3, GRIK2, GRIK5, GRIN1, GRIN2B, NRXN1, PTEN, RELN

Positive regulation of axonogenesis

3.45E−07

ADNP, DSCAM, PLXNA4, PLXNB1, SEMA5A

Regulation of dendritic spine development

8.78E−06

FMR1, MTOR, PTEN, RELN

Regulation of neurotransmitter uptake

4.09E−06

GFAP, PER2, PRKN

Androgen receptor signaling pathway

6.28E−06

CREBBP, CTNNB1, PTEN, UBE3A

Dopamine transport

8.90E−05

CNR1, PRKN, SLC6A3

Corticotropin-releasing hormone signaling pathway

6.85E−06

CACNA1H, CTNNB1, PRKCB, TCF4

Multicellular organismal response to stress

2.61E−07

DEAF1, GRIK2, GRIK5, PTEN, RELN

Regulation of transcription regulatory region DNA binding

2.20E−06

CTNNB1, NSD1, PAX6, PER2

Circadian entrainment

3.41E−09

CACNA1H, GRIA2, GRIN1, GRIN2B, PER2, PRKCB

Wnt signaling pathway

4.50E−15

CTNNB1, MTOR, PRKCB, TCF4, TCF7L2, TEK, TSC1, TSC2

Epithelial cell apoptotic process

3.52E−08

DNMT3A, MTOR, SEMA5A, TCF4, TCF7L2, TEK

Long-term synaptic potentiation

9.54E−09

CHRNA7, GFAP, GRIN2B, NF1, PTEN, RELN