Table 1 Characteristics of the human samples
From: Advanced paternal age as a risk factor for neurodevelopmental disorders: a translational study
| Variable | Mean (SD) |
|---|---|
| Main cohort (N = 677) | |
| Sex ratio (men/women) | 365/312 |
| Age | 26.02 (7.1) |
| Estimated verbal IQ | 111.99 (12.24) |
| Years of education | 15.87 (2.87) |
| Father’s age | 31.34 (5.54) |
| Mother’s age | 28.45 (4.87) |
| Personality | |
| SPQ-B | |
| Cognitive-perceptual deficits | 1.31 (1.38) |
| Interpersonal deficits | 2.02 (1.79) |
| Disorganization | 1.22 (1.43) |
| SPQ-B total score | 4.56 (3.36) |
| NEO-FFI | |
| Neuroticism | 1.43 (.63) |
| Extraversion | 2.26 (.51) |
| Openness | 2.49 (.63) |
| Agreeableness | 2.48 (.67) |
| Conscientiousness | 2.59 (.58) |
| Cognition | |
| d2 test (KL, attention) | 192.7 (37.8) |
| MWT-B (brief verbal IQ) | 30.2 (3.3) |
| Trail-making-test | 28.2 (12.6) |
| Semantic verbal fluency | 25.9 (5.4) |
| Lexical verbal fluency | 14.4 (5.1) |
| Letter-number-span | 16.6 (2.6) |
| Symbol coding | 66.2 (11.2) |
| Spatial span | 18.9 (3.1) |
| VLMT | |
| Learning | 58.6 (7.6) |
| Delayed recall | 12.6 (2.3) |
| VBM sample (N = 342) | |
| Sex ratio (men/women) | 198/144 |
| Age | 27.53 (7.90) |
| Estimated verbal IQ | 115.27 (12.21) |
| Years of education | 13.83 (2.73) |
| Father’s age | 30.67 (5.27) |
| Mother’s age | 28.09 (4.86) |
| DTI sample (N = 222) | |
| Sex ratio (men/women) | 126/96 |
| Age | 26.11 (4.87) |
| Estimated verbal IQ | 114.9 (11.82) |
| Father’s age | 30.56 (5.53) |
| Mother’s age | 28.08 (4.92) |