Table 5 Adverse events

 Leukocytopenia

Mild

2-3

Yes

1

 Hypokalemia

Mild

1-2

Yes

7

 Hyponatremia

Mild

2

Yes

1

 Hypovolemia

Mild

1

Yes

1

 Nausea/vomiting

Mild

3

Yes

1

 Obstipation

Mild

2

Yes

2

 Decreased appetite

Mild

2

No

1

 Weight loss

Mild

2

Yes

1

 Diuresis

Mild

1

Yes

1

 Viral infection

Mild

3

No

1

 Urinary tract infection

Mild

2

No

1

 Aggression

Moderate

2

No

2

 Irritability

Mild

2

No

2

 Anxiety

Mild

2

No

1

Musculoskeletal

1

 Medial malleolus fracture

Moderate

3

No

1

 Humerus fracture

Moderate

3

No

1

 Hypotension

Mild

1

Yes

1

 Hypothermia

Mild

3

No

1

 Dehydration

Mild

1

Yes

1

 Palpitations

Mild

2

No

1