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Table 4 Mismatch negativity (MMN) mean amplitudes and latencies

From: Effects of bumetanide on neurodevelopmental impairments in patients with tuberous sclerosis complex: an open-label pilot study

  TD (n = 35) TSC (n = 8)
Time point D0 D0 D91 D119
Deviant type Amp (SD) Lat (SD) Amp (SD) Lat (SD) Amp (SD) Lat (SD) Amp (SD) Lat (SD)
Standard −1.82 (.92) 255 (21) −1.45 (.46) 253 (34) −1.51 (.52) 261 (12) −1.65 (.74) 258 (34)
Frequency 1.68 (1.22)ab 138 (40) 3.03 (1.75)a 137 (23) −2.75 (1.71) 136 (28) −2.23 (.70) 125 (28)
Duration −1.91 (1.31) 193 (49) 1.71 (1.5)c 206 (28) 3.11 (1.10)c 206 (31) −1.92 (1.15) 203 (20)
Freq/Dur −2.35 (1.15) 130 (29) −2.28 (1.32) 125 (34) −2.64 (1.52) 116 (16) −2.46 (1.19) 122 (25)
  1. Abbreviation: MMN mismatch negativity, Amp amplitude, Lat latency, SD standard deviation, Freq/Dur frequency duration deviant, TD typically developing control group
  2. aSignificant with Bonferroni correction; bgroup effect;ctreatment effect