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Table 4 Mismatch negativity (MMN) mean amplitudes and latencies

From: Effects of bumetanide on neurodevelopmental impairments in patients with tuberous sclerosis complex: an open-label pilot study

 

TD (n = 35)

TSC (n = 8)

Time point

D0

D0

D91

D119

Deviant type

Amp (SD)

Lat (SD)

Amp (SD)

Lat (SD)

Amp (SD)

Lat (SD)

Amp (SD)

Lat (SD)

Standard

−1.82 (.92)

255 (21)

−1.45 (.46)

253 (34)

−1.51 (.52)

261 (12)

−1.65 (.74)

258 (34)

Frequency

−1.68 (1.22)ab

138 (40)

−3.03 (1.75)a

137 (23)

−2.75 (1.71)

136 (28)

−2.23 (.70)

125 (28)

Duration

−1.91 (1.31)

193 (49)

−1.71 (1.5)c

206 (28)

−3.11 (1.10)c

206 (31)

−1.92 (1.15)

203 (20)

Freq/Dur

−2.35 (1.15)

130 (29)

−2.28 (1.32)

125 (34)

−2.64 (1.52)

116 (16)

−2.46 (1.19)

122 (25)

  1. Abbreviation: MMN mismatch negativity, Amp amplitude, Lat latency, SD standard deviation, Freq/Dur frequency duration deviant, TD typically developing control group
  2. aSignificant with Bonferroni correction; bgroup effect;ctreatment effect