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Table 2 Habituation and percentage prepulse-pulse inhibition (PPI)

From: Effects of bumetanide on neurodevelopmental impairments in patients with tuberous sclerosis complex: an open-label pilot study

 TD (n = 31)TSC (n = 7)
Time pointD0D0D91D119
TrialMean % (SD)Mean % (SD)
85dB/120ms34 (33)-9 (52)19 (25)c1 (55)
85dB/60ms30 (35)-13 (45)-15 (16)-12 (45)
76dB/120ms32 (27)ab-24 (58)13 (30)3 (21)
76dB/60ms13 (49)ab-44 (55)-26 (34)-14 (20)
Habituation coefficient-4.52-1.91-6.63ac-.78ac
  1. Abbreviations: TD typically developing controls, TSC tuberous sclerosis complex
  2. asignificant after Bonferroni correction; bgroup effect; ctreatment effect