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Table 2 Habituation and percentage prepulse-pulse inhibition (PPI)

From: Effects of bumetanide on neurodevelopmental impairments in patients with tuberous sclerosis complex: an open-label pilot study

  TD (n = 31) TSC (n = 7)
Time point D0 D0 D91 D119
Trial Mean % (SD) Mean % (SD)
85dB/120ms 34 (33) -9 (52) 19 (25)c 1 (55)
85dB/60ms 30 (35) -13 (45) -15 (16) -12 (45)
76dB/120ms 32 (27)ab -24 (58) 13 (30) 3 (21)
76dB/60ms 13 (49)ab -44 (55) -26 (34) -14 (20)
Habituation coefficient -4.52 -1.91 -6.63ac -.78ac
  1. Abbreviations: TD typically developing controls, TSC tuberous sclerosis complex
  2. asignificant after Bonferroni correction; bgroup effect; ctreatment effect