Skip to main content
Fig. 5 | Molecular Autism

Fig. 5

From: Effects of bumetanide on neurodevelopmental impairments in patients with tuberous sclerosis complex: an open-label pilot study

Fig. 5

a Mean percentage PPI in the TD group and TSC patients for all four prepulse-pulse trials. Significantly less PPI was found in TSC compared with TD in the two 76 dB types at baseline. Improvement was found after treatment in trial-type 85 dB/120 ms. b Startle amplitude measured with electromyography for the 8 trials of blocks 1 and 2 in a habituation paradigm. Increased sensitization is apparent in the TSC group at baseline and habituation changes after treatment (D91) and wash-out (D119)

Back to article page