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Table 1 Demographic characteristics, psychological questionnaire scores, and baseline hormone levels in the autism and neurotypical groups

From: Effects of oxytocin administration on salivary sex hormone levels in autistic and neurotypical women

 AutismNeurotypicalp-valueCohen’s d
N1629  
Demographics
 Age (years)29.9 ± 8.427.2 ± 8.10.310.33
 Full-IQ1121.2 ± 16.4114.6 ± 14.30.190.44
 Hormonal contraceptive use (n)08  
Psychological variables
 Autism-Spectrum Quotient (AQ)37.1 ± 5.114.1 ± 7.5< 0.01**3.4
 Empathy Quotient (EQ)20.7 ± 11.754.6 ± 14.0< 0.01**− 2.5
Baseline hormone levels2
 Baseline oestradiol (pg/ml)1.0 ± 0.31.2 ± 0.50.055− 0.54
 Baseline testosterone (pg/ml)70.3 ± 24.966.4 ± 22.00.600.17
 T:E2 ratio30.39 ± 0.63− 0.22 ± 1.10.023 *0.63
 Baseline oxytocin (pg/ml)3.1 ± 0.52.8 ± 0.60.0640.57
  1. Values are mean ± SD, unless otherwise specified
  2. *p < 0.05, **p < 0.01
  3. 1Wechsler Abbreviated Scale of Intelligence
  4. 2Baseline hormone levels were calculated as the mean of the two pre-administration samples collected per participant
  5. 3Log-transformed and then normalised to have mean of 0 and standard deviation of 1